What support and resources
    are available?

    What is KaryForward®, and how do I join?

    KaryForward is a patient support program by Karyopharm Therapeutics® Inc. dedicated to
    providing assistance and resources to you and your caregiver for XPOVIO® (selinexor).

    KaryForward can help you with:

    Insurance coverage icon

    Insurance coverage*

    • Understand your benef‌its
    • File claims
    • Provide support during insurance appeals
    • Find out what is covered by your insurance
    • Access Karyopharm medications, even if there are unexpected delays or interruptions
    Financial assistance icon

    Financial assistance

    • Qualify for the XPOVIO Copay Program and pay as little as $5 for each XPOVIO prescription, or
    • If eligible, get XPOVIO at no cost to you
    Support and resources icon

    Support and resources

    • Nurse Case Managers who can provide education and support during treatment
    • Referrals to additional third-party support such as transportation assistance

    *Reimbursement Specialists are available to answer questions about the insurance approval process.

    If you’re ready to enroll or have questions about KaryForward, visit KaryForward.com
    or call 1‑877‑KARY4WD1‑877‑KARY4WD (1-877-527-9493), Monday through Friday, 8 am to 8 pm ET

    How do I take care of myself when I’m caring for someone taking XPOVIO?

    • Taking care of a loved one with relapsed or refractory dif‌fuse large B-cell lymphoma (RR DLBCL) can be emotionally and physically demanding. It’s important not to lose sight of your own well-being
    • A support group that’s online or in your local area may help you connect with people who understand what you’re going through
    • Your loved one’s healthcare providers and social worker are there for you to answer your questions or support your needs
    • Doing activities like yoga and meditation may help relieve stress

    What else should I know about caring for someone taking XPOVIO?

    When caring for a patient taking XPOVIO, keep in mind:

    • The healthcare provider will determine the dosing schedule for XPOVIO and anti-nausea medicine
    • Call the healthcare provider if your loved one experiences any side ef‌fects
    • The healthcare team will do blood tests before your loved one starts taking XPOVIO, more often during the f‌irst 3 months of treatment, and then as needed
    • Encourage your loved one to drink lots of f‌luids and eat nutritious food while on XPOVIO

    For more information about caring for a loved one, visit these organizations:

    Helpful tools and resources

    Whether you’re living with RR DLBCL or supporting a loved one with RR DLBCL, it’s important to remember that you’re not alone. There are a number of valuable resources and organizations available to help. Use the following materials and links to get the support you need and deserve:

    Patient brochure thumbnail
    Patient Brochure

    Get information about treatment with XPOVIO

    Download
    KaryFORWARD™ enrollment form thumbnail
    KaryForward Enrollment Form

    Enroll in KaryForward, a patient support program

    Download

    Helpful organizations and support

    In addition to your healthcare team, the following organizations may be helpful resources:

    DLBCL Resources

    Leukemia & Lymphoma Society

    www.lls.org

    800-955-4572

    Lymphoma Coalition

    www.lymphomacoalition.org

    Lymphoma Research Foundation

    www.lymphoma.org

    800-500-9976

    Caregiver Support Resources

    Caregiver Action Network

    www.caregiveraction.org

    202-454-3970

    Family Caregiver Alliance

    www.caregiver.org

    800-445-8106

    Cancer Resources

    American Cancer Society

    www.cancer.org

    800-227-2345

    CancerCare

    www.cancercare.org

    800-813-HOPE (4673)

    Cancer Hope Network

    www.cancerhopenetwork.org

    877-HOPENET (467-3638)

    Cancer Support Community

    www.cancersupportcommunity.org

    888-793-9355

    In order to maintain the independence of these organizations, Karyopharm does not endorse or recommend any of the advocacy groups or services on this list and is not responsible for the content of these sites or services. Always talk to your healthcare team about any questions.

    What is XPOVIO?

    XPOVIO® (selinexor) is a prescription medicine used:

    • in combination with dexamethasone to treat adults with multiple myeloma (MM) that has come back (relapsed) or that did not respond to previous treatment (refractory), and
      • who have received at least 4 prior therapies, and
      • whose disease did not respond (refractory) to at least 2 proteasome inhibitor medicines, at least 2 immunomodulatory agents, and an anti-CD38 monoclonal antibody medicine

    What is the most important information I should know about XPOVIO?

    Your healthcare provider will do blood tests before you start taking XPOVIO, and often during the first 3 months of treatment, and then as needed during treatment to monitor you for side effects. Your healthcare provider may change your dose of XPOVIO, stop your treatment for a period of time, or completely stop your treatment if you have certain side effects during treatment with XPOVIO.