What support and resources
    are available?

    KaryForward is a patient support program by Karyopharm Therapeutics® Inc. dedicated to providing assistance and resources to you and your caregiver for XPOVIO® (selinexor).

    The KaryForward program is here to help you every step of the way with your treatment journey. We can assist you with:

    Insurance coverage icon

    Insurance coverage*

    • Understand your benefits
    • File claims
    • Provide support during insurance appeals
    • Find out what is covered by your insurance
    • Access Karyopharm medications, even if there are unexpected delays or interruptions
    Financial assistance icon

    Financial assistance

    • Qualify for the XPOVIO Copay Program and pay as little as $5 for each XPOVIO prescription
    • OR
    • If eligible, get XPOVIO at no cost to you
    Support and resources icon

    Resources and support

    You’ll have access to a dedicated Nurse Case Manager who can:

    • Provide personalized support and education during treatment
    • Provide prescription instructions
    • Offer psychosocial support and additional nonclinical education
    • Highlight what to expect when taking Karyopharm medication and the importance of talking to healthcare providers about the treatment journey
    • Determine if additional third-party support is available such as transportation assistance

    *Reimbursement Specialists are available to answer questions about the insurance approval process.

    If you’re ready to enroll or have questions about KaryForward, visit KaryForward.com or call 1-877-KARY4WD1-877-KARY4WD (1-877-527-9493), Monday through Friday, 8 am to 8 pm ET

    How do I take care of myself when I’m caring for someone taking XPOVIO?

    The physical and emotional demands of being a caregiver can take a toll over time

    You may experience:

    • Exhaustion
    • Getting sick more often
    • Losing sleep
    • Irritation

    Tips for caring for yourself include:

    • Consider finding a support group online or in your local area, or connect with people who understand what you may be going through
      Learn about a variety of support groups
    • If you have questions or support needs, talk to the nurse, social worker, or your loved one’s healthcare provider
    • Consider practicing yoga or meditation to help relieve stress

    Track Monthly Appointments

    The Caregiver Monthly Planner helps you track upcoming appointments and important To Do’s

    What else should I know about caring for someone taking XPOVIO?

    When caring for a person taking XPOVIO, keep in mind:

    • The healthcare provider will determine the dosing schedule for XPOVIO, dexamethasone, and anti-nausea medicine
    • Call the healthcare provider if your loved one experiences any side effects
    • The healthcare provider will do blood tests before your loved one starts taking XPOVIO, often during the 3 months of treatment, and then as needed
    • Encourage your loved one to drink lots of fluids and eat nutritious food while on XPOVIO

    Join the KaryForward Support Program and you and your loved ones will receive:

    • Helpful caregiver resources
    • XPOVIO Patient Education Starter Kit
    • Personalized support from Nurse Case Managers
    • Information about financial resources

    Helpful tools and resources

    Whether you’re living with relapsed or refractory multiple myeloma (RRMM) or supporting a loved one with RRMM, it’s important to remember that you’re not alone. There are a number of valuable resources and organizations available to help. Use the following materials and links to get the support you need and deserve.

    Patient & caregiver brochure
    Patient & Caregiver Brochure

    Get information about treatment with XPOVIO

    Download [English] Download [Spanish]
    Patient daily tracker
    Patient Daily Tracker

    A helpful tool for tracking medication as well as fluid and caloric intake

    Download [English] Download [Spanish]
    Caregiver monthly planner
    Caregiver Monthly Planner

    Keep track of monthly appointments

    Download [English] Download [Spanish]
    KaryForward enrollment form
    KaryForward Enrollment Form

    Enroll in KaryForward, a patient support program

    Download [English]

    Helpful organizations and support

    In addition to your healthcare team, the following organizations may be helpful resources.

    Multiple Myeloma Resources

    International Myeloma Foundation


    800-452-CURE (2873)

    Multiple Myeloma Research Foundation


    866-603-MMCT (6628)

    Caregiver Support Resources

    Caregiver Action Network



    Family Caregiver Alliance



    Cancer Resources

    American Cancer Society





    800-813-HOPE (4673)

    Cancer Hope Network


    877-HOPENET (467-3638)

    Cancer Support Community



    To maintain the independence of these organizations, Karyopharm does not endorse or recommend any of the advocacy groups or services on this list and is not responsible for the content of these sites or services. Always talk to your healthcare team about any questions.

    What is XPOVIO?

    XPOVIO® (selinexor) is a prescription medicine used:

    • in combination with dexamethasone to treat adults with multiple myeloma (MM) that has come back (relapsed) or that did not respond to previous treatment (refractory), and
      • who have received at least 4 prior therapies, and
      • whose disease did not respond (refractory) to at least 2 proteasome inhibitor medicines, at least 2 immunomodulatory agents, and an anti-CD38 monoclonal antibody medicine

    What is the most important information I should know about XPOVIO?

    Your healthcare provider will do blood tests before you start taking XPOVIO, and often during the first 3 months of treatment, and then as needed during treatment to monitor you for side ef‍fects. Your healthcare provider may change your dose of XPOVIO, stop your treatment for a period of time, or completely stop your treatment if you have certain side ef‍fects during treatment with XPOVIO.